Golden Globes host Nikki Glaser mocks Diddy, Ben Affleck in opening monologue

Ariana Grande, Selena Gomez nominated at 2025 Golden Globes in Los Angeles

Golden Globes, watch out – Nikki Glaser is here to host.

Glaser, 40, opened the show with a nod to weight-loss medication, announcing it was “Ozempic’s biggest night.”

While onstage live from the Beverly Hilton hotel in Beverly Hills, Calif., Glaser commended Zendaya for her role in “Challengers,” which follows the tennis ace in a love triangle with her husband and ex-boyfriend.